Cupramine Copper Medication – Seachem




CupramineTM effectively eradicates Oodinium, Cryptocaryon, Amyloodinium, Ichthyophthirius, and other ectoparasites of both freshwater and marine fish. It is superior to copper sulfate, chloride & citrate: it is non-acidic, less toxic to fish, remains in solution, and does not contaminate the filter bed. It is superior to chelates: it is fully charged (ionic), active at low concentrations, and is removable with carbon.

There is more than a four-fold concentration gap between the minimal therapeutic dose (0.2 mg/L) and the toxic dose (0.8 mg/L). CupramineTM is easily removable with chemical filtration. It is highly effective and protected in freshwater as well as marine water.

DirectionsBefore Treating

Remove all invertebrates – these are extremely sensitive to copper and will not tolerate remedy with a copper-based medication. Turn off UV filters, ozone filters, and remove chemical filtration like MatrixCarbon and Purigen. Do not use at the side of any other medication. Do not use any products which contain reducing agents (conditioners, ammonia binders, etc.) whilst the use of Cupramine.


If the bottle has a dropper cap, use 20 drops (1 mL) per 40 L (10.5 US gallons) the first day, wait 48 hours, then repeat. On non-dropper caps, each inner ring is 1 mL. In freshwater use half dose. Final copper concentration is 0.5 mg/L (0.25 mg/L in freshwater). Leave at this concentration for 14 days. Do not redose without testing (MultiTestTM: Copper). If tank has ever been treated with an ionic copper (e.g. copper chloride, sulfate or citrate), test copper level after initial dosing. Even if most fish tolerate CupramineTM to 0.8 mg/L, it is not advisable to exceed 0.6 mg/L copper.

Finish the Full Treatment

Ich, velvet, and many other parasites spend a large portion of their life cycle as a cyst that is immune to medication and hiding in the substrate of your tank. Keep in mind that you want to finish the full remedy although you’ll be able to


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